Monitoring BRAF and NRAS mutations with cell-free circulating tumor DNA from metastatic melanoma patients

The mutation status of the BRAF and NRAS genes in tumor tissue is used to select patients with metastatic melanoma for targeted therapy. Cell-free circulating DNA (cfDNA) represents an accessible, non-invasive surrogate sample that could provide a snapshot of the BRAF and NRAS genotype in these pati...

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Vydáno v:Oncotarget
Hlavní autoři: Long-Mira, Elodie, Ilie, Marius, Chamorey, Emmanuel, Leduff-Blanc, Florence, Montaudié, Henri, Tanga, Virginie, Allégra, Maryline, Lespinet-Fabre, Virginie, Bordone, Olivier, Bonnetaud, Christelle, Schiappa, Renaud, Butori, Catherine, Bence, Coraline, Lacour, Jean-Philippe, Hofman, Véronique, Hofman, Paul
Médium: Artigo
Jazyk:Inglês
Vydáno: Impact Journals LLC 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281416/
https://ncbi.nlm.nih.gov/pubmed/30546839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26343
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