Monitoring BRAF and NRAS mutations with cell-free circulating tumor DNA from metastatic melanoma patients

The mutation status of the BRAF and NRAS genes in tumor tissue is used to select patients with metastatic melanoma for targeted therapy. Cell-free circulating DNA (cfDNA) represents an accessible, non-invasive surrogate sample that could provide a snapshot of the BRAF and NRAS genotype in these pati...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Long-Mira, Elodie, Ilie, Marius, Chamorey, Emmanuel, Leduff-Blanc, Florence, Montaudié, Henri, Tanga, Virginie, Allégra, Maryline, Lespinet-Fabre, Virginie, Bordone, Olivier, Bonnetaud, Christelle, Schiappa, Renaud, Butori, Catherine, Bence, Coraline, Lacour, Jean-Philippe, Hofman, Véronique, Hofman, Paul
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2018
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281416/
https://ncbi.nlm.nih.gov/pubmed/30546839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26343
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