Monitoring BRAF and NRAS mutations with cell-free circulating tumor DNA from metastatic melanoma patients

The mutation status of the BRAF and NRAS genes in tumor tissue is used to select patients with metastatic melanoma for targeted therapy. Cell-free circulating DNA (cfDNA) represents an accessible, non-invasive surrogate sample that could provide a snapshot of the BRAF and NRAS genotype in these pati...

詳細記述

保存先:
書誌詳細
出版年:Oncotarget
主要な著者: Long-Mira, Elodie, Ilie, Marius, Chamorey, Emmanuel, Leduff-Blanc, Florence, Montaudié, Henri, Tanga, Virginie, Allégra, Maryline, Lespinet-Fabre, Virginie, Bordone, Olivier, Bonnetaud, Christelle, Schiappa, Renaud, Butori, Catherine, Bence, Coraline, Lacour, Jean-Philippe, Hofman, Véronique, Hofman, Paul
フォーマット: Artigo
言語:Inglês
出版事項: Impact Journals LLC 2018
主題:
Research Paper
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281416/
https://ncbi.nlm.nih.gov/pubmed/30546839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.26343
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