During Hepatitis C Virus (HCV) Infection and HCV-HIV Coinfection, an Elevated Plasma Level of Autotaxin Is Associated With Lysophosphatidic Acid and Markers of Immune Activation That Normalize During Interferon-Free HCV Therapy

Background. Immune activation predicts morbidity during hepatitis C virus (HCV) infection and human immunodeficiency virus (HIV) infection, although mechanisms underlying immune activation are unclear. Plasma levels of autotaxin and its enzymatic product, lysophosphatidic acid (LPA), are elevated du...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Kostadinova, Lenche, Shive, Carey L., Judge, Chelsey, Zebrowski, Elizabeth, Compan, Anita, Rife, Kelsey, Hirsch, Amy, Falck-Ytter, Yngve, Schlatzer, Daniela M., Li, Xiaolin, Chance, Mark R., Rodriguez, Benigno, Popkin, Daniel L, Anthony, Donald D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2016
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281372/
https://ncbi.nlm.nih.gov/pubmed/27540113
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw372
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