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Wnt11 directs nephron progenitor polarity and motile behavior ultimately determining nephron endowment
A normal endowment of nephrons in the mammalian kidney requires a balance of nephron progenitor self-renewal and differentiation throughout development. Here, we provide evidence for a novel action of ureteric branch tip-derived Wnt11 in progenitor cell organization and interactions within the nephr...
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| Veröffentlicht in: | eLife |
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| Hauptverfasser: | , , , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
eLife Sciences Publications, Ltd
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6281319/ https://ncbi.nlm.nih.gov/pubmed/30516471 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.40392 |
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