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Analysis of NK cell clones obtained using interleukin-2 and gene-modified K562 cells revealed the ability of “senescent” NK cells to lose CD57 expression and start expressing NKG2A

In this work, we analyzed the phenotype and growth of human NK cell clones obtained by the stimulation of individual NK cells with IL-2 and gene-modified K562 feeder cells expressing membrane-bound IL-21 (K562-mbIL21). We generated clones from NK cells at distinct differentiation and activation stag...

詳細記述

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書誌詳細
出版年:PLoS One
主要な著者: Streltsova, Maria A., Erokhina, Sofya A., Kanevskiy, Leonid M., Lee, Dean A., Telford, William G., Sapozhnikov, Alexander M., Kovalenko, Elena I.
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281266/
https://ncbi.nlm.nih.gov/pubmed/30517188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0208469
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