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Improving the calling of non-invasive prenatal testing on 13-/18-/21-trisomy by support vector machine discrimination

With the advance of next-generation sequencing (NGS) technologies, non-invasive prenatal testing (NIPT) has been developed and employed in fetal aneuploidy screening on 13-/18-/21-trisomies through detecting cell-free fetal DNA (cffDNA) in maternal blood. Although Z-test is widely used in NIPT NGS d...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Yang, Jianfeng, Ding, Xiaofan, Zhu, Weidong
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281214/
https://ncbi.nlm.nih.gov/pubmed/30517156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207840
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