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Improving the calling of non-invasive prenatal testing on 13-/18-/21-trisomy by support vector machine discrimination

With the advance of next-generation sequencing (NGS) technologies, non-invasive prenatal testing (NIPT) has been developed and employed in fetal aneuploidy screening on 13-/18-/21-trisomies through detecting cell-free fetal DNA (cffDNA) in maternal blood. Although Z-test is widely used in NIPT NGS d...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Yang, Jianfeng, Ding, Xiaofan, Zhu, Weidong
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6281214/
https://ncbi.nlm.nih.gov/pubmed/30517156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0207840
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