Sarcosine Is Uniquely Modulated by Aging and Dietary Restriction in Rodents and Humans

A hallmark of aging is a decline in metabolic homeostasis, which is attenuated by dietary restriction (DR). However, the interaction of aging and DR with the metabolome is not well understood. We report that DR is a stronger modulator of the rat metabolome than age in plasma and tissues. A comparati...

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Opis bibliograficzny
Wydane w:Cell Rep
Główni autorzy: Walters, Ryan O., Arias, Esperanza, Diaz, Antonio, Burgos, Emmanuel S., Guan, Fangxia, Tiano, Simoni, Mao, Kai, Green, Cara L., Qiu, Yungping, Shah, Hardik, Wang, Donghai, Hudgins, Adam D., Tabrizian, Tahmineh, Tosti, Valeria, Shechter, David, Fontana, Luigi, Kurland, Irwin J., Barzilai, Nir, Cuervo, Ana Maria, Promislow, Daniel E.L., Huffman, Derek M.
Format: Artigo
Język:Inglês
Wydane: 2018
Hasła przedmiotowe:
Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280974/
https://ncbi.nlm.nih.gov/pubmed/30332646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.09.065
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