Population pharmacokinetic modeling of flurbiprofen, the active metabolite of flurbiprofen axetil, in Chinese patients with postoperative pain

BACKGROUND: Flurbiprofen axetil, a lipid-microsphere-carrier targeting preparation, is a non-steroidal anti-inflammatory drug indicated for the treatment of postoperative pain. AIM: The aim of the study was to develop a population pharmacokinetic (PPK) model of flurbiprofen, the active metabolite of...

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Vydáno v:J Pain Res
Hlavní autoři: Zhang, Jingru, Zhang, Hong, Zhao, Libo, Gu, Jian, Feng, Yi, An, Haiyan
Médium: Artigo
Jazyk:Inglês
Vydáno: Dove Medical Press 2018
Témata:
Original Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280896/
https://ncbi.nlm.nih.gov/pubmed/30555252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/JPR.S176475
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