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Agglomerated novel spray-dried lactose-leucine tailored as a carrier to enhance the aerosolization performance of salbutamol sulfate from DPI formulations

Spray-drying allows to modify the physicochemical/mechanical properties of particles along with their morphology. In the present study, (L)-leucine with varying concentrations (0.1, 0.5, 1, 5, and 10% w/v) were incorporated into lactose monohydrate solution for spray-drying to enhance the aerosoliza...

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Vydáno v:Drug Deliv Transl Res
Hlavní autoři: Molina, Carlos, Kaialy, Waseem, Chen, Qiao, Commandeur, Daniel, Nokhodchi, Ali
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280810/
https://ncbi.nlm.nih.gov/pubmed/29260462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13346-017-0462-8
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