BRCA1 and BARD1 mediate apoptotic resistance but not longevity upon mitochondrial stress in Caenorhabditis elegans

Interventions that promote healthy aging are typically associated with increased stress resistance. Paradoxically, reducing the activity of core biological processes such as mitochondrial or insulin metabolism promotes the expression of adaptive responses, which in turn increase animal longevity and...

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Detalhes bibliográficos
Publicado no:EMBO Rep
Main Authors: Torgovnick, Alessandro, Schiavi, Alfonso, Shaik, Anjumara, Kassahun, Henok, Maglioni, Silvia, Rea, Shane L, Johnson, Thomas E, Reinhardt, Hans C, Honnen, Sebastian, Schumacher, Björn, Nilsen, Hilde, Ventura, Natascia
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280797/
https://ncbi.nlm.nih.gov/pubmed/30366941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201845856
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