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Role for intraflagellar transport in building a functional transition zone
Genetic disorders caused by cilia dysfunction, termed ciliopathies, frequently involve the intraflagellar transport (IFT) system. Mutations in IFT subunits—including IFT‐dynein motor DYNC2H1—impair ciliary structures and Hedgehog signalling, typically leading to “skeletal” ciliopathies such as Jeune...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6280794/ https://ncbi.nlm.nih.gov/pubmed/30429209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201845862 |
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