Preclinical Studies Support Combined Inhibition of BET Family Proteins and Histone Deacetylases as Epigenetic Therapy for Cutaneous T-Cell Lymphoma()()

Advanced-stage cutaneous T-cell lymphoma (CTCL) is usually a fatal malignancy despite optimal use of currently available treatments. In this preclinical study of novel CTCL therapy, we performed in vitro and ex vivo experiments to determine the efficacy of combination treatment with a panel of BET b...

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Publicat a:Neoplasia
Autors principals: Zhao, Lei, Okhovat, Jean-Phillip, Hong, Eric K., Kim, Youn H., Wood, Gary S.
Format: Artigo
Idioma:Inglês
Publicat: Neoplasia Press 2018
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Original article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6280696/
https://ncbi.nlm.nih.gov/pubmed/30529073
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2018.11.006
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