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4-N-Alkanoyl and 4-N-Alkyl Gemcitabine Analogues with NOTA Chelators for 68-Gallium Labelling
The conjugation of 4-N-(3-aminopropanyl)-2’-deoxy-2’,2’-difluorocytidine with 2-(p-isothiocyanatobenzyl)-1,4,7-triazacyclononane-1,4,7-triacetic acid (SCN-Bn-NOTA) ligand in 0.1 M Na(2)CO(3) buffer (pH 11) at ambient temperature provided 4-N-alkylgemcitabine-NOTA chelator. Incubation of latter with...
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| Publicado no: | Bioorg Med Chem |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6280190/ https://ncbi.nlm.nih.gov/pubmed/30342865 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2018.10.007 |
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