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Pathway sensor-based functional genomics screening identifies modulators of neuronal activity

Neuronal signal transduction shapes brain function and malfunction may cause mental disorders. Despite the existence of functional genomics screens for proliferation and toxicity, neuronal signalling has been difficult to address so far. To overcome this limitation, we developed a pooled screening a...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Herholt, Alexander, Brankatschk, Ben, Kannaiyan, Nirmal, Papiol, Sergi, Wichert, Sven P., Wehr, Michael C., Rossner, Moritz J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279925/
https://ncbi.nlm.nih.gov/pubmed/30514868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36008-9
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