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Multiplexed profiling of GPCR activities by combining split TEV assays and EXT-based barcoded readouts

G protein-coupled receptors (GPCRs) are the largest class of cell surface receptors and are implicated in the physiological regulation of many biological processes. The high diversity of GPCRs and their physiological functions make them primary targets for therapeutic drugs. For the generation of no...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Galinski, Sabrina, Wichert, Sven P., Rossner, Moritz J., Wehr, Michael C.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5970223/
https://ncbi.nlm.nih.gov/pubmed/29802268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-26401-9
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