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Long-term Tumor Adaptation after Radiotherapy: Therapeutic Implications for Targeting Integrins in Prostate Cancer

Adaptation of tumor cells to radiation therapy induces changes that are actionable by molecular targeted agents and immunotherapy. This report demonstrates that radiation-induced changes in integrin expression can be targeted two months later. Integrins are transmembrane cell adhesion molecules whic...

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Dettagli Bibliografici
Pubblicato in:Mol Cancer Res
Autori principali: Eke, Iris, Makinde, Adeola Y., Aryankalayil, Molykutty J., Reedy, Jessica L., Citrin, Deborah E., Chopra, Sunita, Ahmed, Mansoor M., Coleman, C. Norman
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279542/
https://ncbi.nlm.nih.gov/pubmed/30042176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0232
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