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Long-term Tumor Adaptation after Radiotherapy: Therapeutic Implications for Targeting Integrins in Prostate Cancer

Adaptation of tumor cells to radiation therapy induces changes that are actionable by molecular targeted agents and immunotherapy. This report demonstrates that radiation-induced changes in integrin expression can be targeted two months later. Integrins are transmembrane cell adhesion molecules whic...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Eke, Iris, Makinde, Adeola Y., Aryankalayil, Molykutty J., Reedy, Jessica L., Citrin, Deborah E., Chopra, Sunita, Ahmed, Mansoor M., Coleman, C. Norman
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279542/
https://ncbi.nlm.nih.gov/pubmed/30042176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-18-0232
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