CNBP controls IL-12 gene transcription and Th1 immunity

An inducible program of inflammatory gene expression is a hallmark of antimicrobial defenses. Recently, cellular nucleic acid–binding protein (CNBP) was identified as a regulator of nuclear factor-kappaB (NF-κB)–dependent proinflammatory cytokine gene expression. Here, we generated mice lacking CNBP...

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Vydáno v:J Exp Med
Hlavní autoři: Chen, Yongzhi, Sharma, Shruti, Assis, Patricia A., Jiang, Zhaozhao, Elling, Roland, Olive, Andrew J., Hang, Saiyu, Bernier, Jennifer, Huh, Jun R., Sassetti, Christopher M., Knipe, David M., Gazzinelli, Ricardo T., Fitzgerald, Katherine A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Rockefeller University Press 2018
Témata:
Research Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279399/
https://ncbi.nlm.nih.gov/pubmed/30442645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181031
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