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The E3 ligase VHL controls alveolar macrophage function via metabolic–epigenetic regulation

Metabolic pathways such as glycolysis or oxidative phosphorylation play a key role in regulating macrophage function during inflammation and tissue repair. However, how exactly the VHL–HIF–glycolysis axis is involved in the function of tissue-resident macrophages remains unclear. Here we demonstrate...

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Detalhes bibliográficos
Publicado no:J Exp Med
Main Authors: Zhang, Wen, Li, Qian, Li, Dulei, Li, Jia, Aki, Daisuke, Liu, Yun-Cai
Formato: Artigo
Idioma:Inglês
Publicado em: Rockefeller University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279396/
https://ncbi.nlm.nih.gov/pubmed/30463876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20181211
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