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Insight into human alveolar macrophage and M. tuberculosis interactions via metabolic reconstructions

Metabolic coupling of Mycobacterium tuberculosis to its host is foundational to its pathogenesis. Computational genome-scale metabolic models have shown utility in integrating -omic as well as physiologic data for systemic, mechanistic analysis of metabolism. To date, integrative analysis of host–pa...

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Bibliografiske detaljer
Main Authors: Bordbar, Aarash, Lewis, Nathan E, Schellenberger, Jan, Palsson, Bernhard Ø, Jamshidi, Neema
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2990636/
https://ncbi.nlm.nih.gov/pubmed/20959820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/msb.2010.68
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