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Splicing of an automodulatory domain in Ca(v)1.4 Ca(2+) channels confers distinct regulation by calmodulin

Ca(2+) influx through Ca(v)1.4 L-type Ca(2+) channels supports the sustained release of glutamate from photoreceptor synaptic terminals in darkness, a process that is critical for vision. Consistent with this role, Ca(v)1.4 exhibits weak Ca(2+)-dependent inactivation (CDI)—a negative feedback regula...

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Bibliografiske detaljer
Udgivet i:J Gen Physiol
Main Authors: Williams, Brittany, Haeseleer, Françoise, Lee, Amy
Format: Artigo
Sprog:Inglês
Udgivet: Rockefeller University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279360/
https://ncbi.nlm.nih.gov/pubmed/30355583
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812140
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