Differential modulation of Ca(v)2.1 channels by calmodulin and Ca(2+)-binding protein 1

Ca(v)2.1 channels, which mediate P/Q-type Ca(2+) currents, undergo Ca(2+)/calmodulin (CaM)-dependent inactivation and facilitation that can significantly alter synaptic efficacy. Here we report that the neuronal Ca(2+)-binding protein 1 (CaBP1) modulates Ca(v)2.1 channels in a manner that is markedl...

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Bibliographic Details
Main Authors: Lee, Amy, Westenbroek, Ruth E., Haeseleer, Françoise, Palczewski, Krzysztof, Scheuer, Todd, Catterall, William A.
Format: Artigo
Language:Inglês
Published: 2002
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1435861/
https://ncbi.nlm.nih.gov/pubmed/11865310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nn805
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