Fragile X mental retardation protein is a Zika virus restriction factor that is antagonized by subgenomic flaviviral RNA

Subgenomic flaviviral RNA (sfRNA) accumulates during infection due to incomplete degradation of viral genomes and interacts with cellular proteins to promote infection. Here we identify host proteins that bind the Zika virus (ZIKV) sfRNA. We identified fragile X mental retardation protein (FMRP) as...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Soto-Acosta, Ruben, Xie, Xuping, Shan, Chao, Baker, Coleman K, Shi, Pei-Yong, Rossi, Shannan L, Garcia-Blanco, Mariano A, Bradrick, Shelton
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2018
Konular:
Chromosomes and Gene Expression
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279352/
https://ncbi.nlm.nih.gov/pubmed/30511641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39023
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