Fragile X mental retardation protein is a Zika virus restriction factor that is antagonized by subgenomic flaviviral RNA

Subgenomic flaviviral RNA (sfRNA) accumulates during infection due to incomplete degradation of viral genomes and interacts with cellular proteins to promote infection. Here we identify host proteins that bind the Zika virus (ZIKV) sfRNA. We identified fragile X mental retardation protein (FMRP) as...

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Dades bibliogràfiques
Publicat a:eLife
Autors principals: Soto-Acosta, Ruben, Xie, Xuping, Shan, Chao, Baker, Coleman K, Shi, Pei-Yong, Rossi, Shannan L, Garcia-Blanco, Mariano A, Bradrick, Shelton
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2018
Matèries:
Chromosomes and Gene Expression
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279352/
https://ncbi.nlm.nih.gov/pubmed/30511641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39023
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