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Knotty Zika virus blocks exonuclease to produce subgenomic flaviviral RNAs
In a recent issue of Science, Akiyama et al. (2016) prove the existence of a pseudoknot that stabilizes a nuclease-resistant RNA structure in the 3’ untranslated region of Zika virus. This reinforced structure blocks the 5’→3’ exonuclease Xrn1 for the production of pathogenic subgenomic flaviviral R...
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| Publicado no: | Cell Host Microbe |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6123830/ https://ncbi.nlm.nih.gov/pubmed/28081439 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2016.12.013 |
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