Lipidation-independent vacuolar functions of Atg8 rely on its noncanonical interaction with a vacuole membrane protein

The ubiquitin-like protein Atg8, in its lipidated form, plays central roles in autophagy. Yet, remarkably, Atg8 also carries out lipidation-independent functions in non-autophagic processes. How Atg8 performs its moonlighting roles is unclear. Here we report that in the fission yeast Schizosaccharom...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Liu, Xiao-Man, Yamasaki, Akinori, Du, Xiao-Min, Coffman, Valerie C, Ohsumi, Yoshinori, Nakatogawa, Hitoshi, Wu, Jian-Qiu, Noda, Nobuo N, Du, Li-Lin
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279349/
https://ncbi.nlm.nih.gov/pubmed/30451685
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41237
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