Φορτώνει......
CD27 stimulation unveils the efficacy of linked class I/II peptide vaccines in poorly immunogenic tumors by orchestrating a coordinated CD4/CD8 T cell response
Despite their promise, tumor-specific peptide vaccines have limited efficacy. CD27 is a costimulatory molecule expressed on CD4(+) and CD8(+) T cells that is important in immune activation. Here we determine if a novel CD27 agonist antibody (αhCD27) can enhance the antitumor T cell response and effi...
Αποθηκεύτηκε σε:
Τόπος έκδοσης: | Oncoimmunology |
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Κύριοι συγγραφείς: | , , , , , , , , , , , , |
Μορφή: | Artigo |
Γλώσσα: | Inglês |
Έκδοση: |
Taylor & Francis
2018
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Θέματα: | |
Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6279317/ https://ncbi.nlm.nih.gov/pubmed/30524899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2018.1502904 |
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