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Lhx8 ablation leads to massive autophagy of mouse oocytes associated with DNA damage()

Following proliferation of oogonia in mammals, great numbers of germ cells are discarded, primarily by apoptosis, while the remainder form primordial follicles (the ovarian reserve) that determine fertility and reproductive lifespan. More massive, rapid, and essentially total loss of oocytes, howeve...

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Detalhes bibliográficos
Publicado no:Biol Reprod
Main Authors: D’Ignazio, Laura, Michel, Marc, Beyer, Melissa, Thompson, Kassimier, Forabosco, Antonino, Schlessinger, David, Pelosi, Emanuele
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279113/
https://ncbi.nlm.nih.gov/pubmed/29329412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/iox184
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