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Lhx8 ablation leads to massive autophagy of mouse oocytes associated with DNA damage()

Following proliferation of oogonia in mammals, great numbers of germ cells are discarded, primarily by apoptosis, while the remainder form primordial follicles (the ovarian reserve) that determine fertility and reproductive lifespan. More massive, rapid, and essentially total loss of oocytes, howeve...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Biol Reprod
Prif Awduron: D’Ignazio, Laura, Michel, Marc, Beyer, Melissa, Thompson, Kassimier, Forabosco, Antonino, Schlessinger, David, Pelosi, Emanuele
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Oxford University Press 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279113/
https://ncbi.nlm.nih.gov/pubmed/29329412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/iox184
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