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A phase I study of cabozantinib (XL184) in patients with renal cell cancer

BACKGROUND: Cabozantinib targets tyrosine kinases including the hepatocyte growth factor receptor (MET) and vascular endothelial growth factor (VEGF) receptor 2, which are important drug targets in renal cell carcinoma (RCC). PATIENTS AND METHODS: This single-arm open-label phase I trial evaluated t...

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Publicat a:Ann Oncol
Autors principals: Choueiri, T. K., Pal, S. K., McDermott, D. F., Morrissey, S., Ferguson, K. C., Holland, J., Kaelin, W. G., Dutcher, J. P.
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279111/
https://ncbi.nlm.nih.gov/pubmed/24827131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/annonc/mdu184
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