Hyperandrogenemia reduces endothelium-derived hyperpolarizing factor-mediated relaxation in mesenteric artery of female rats(†)

Women with polycystic ovary syndrome (PCOS) are often presented with hyperandrogenemia along with vascular dysfunction and elevated blood pressure. In animal models of PCOS, anti-androgen treatment decreased blood pressure, indicating a key role for androgens in the development of hypertension. Howe...

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Udgivet i:Biol Reprod
Main Authors: Mishra, Jay S., More, Amar S., Hankins, Gary D. V., Kumar, Sathish
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
Mechanisms of Hormone Action
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6279110/
https://ncbi.nlm.nih.gov/pubmed/28486649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biolre/iox043
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