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Endothelium-dependent hyperpolarization and relaxation in mesenteric arteries of middle-aged rats: influence of oestrogen

1. We determined whether gender and/or oestrogen deficiency affect endothelium-dependent hyperpolarization and relaxation in mesenteric arteries isolated from middle-aged (44 – 45 week old) rats. 2. The hyperpolarizing response to acetylcholine (ACh) was significantly greater in females than in male...

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Detalhes bibliográficos
Main Authors: Sakuma, Ichiro, Liu, Ming-Yue, Sato, Atsushi, Hayashi, Toshio, Iguchi, Akihisa, Kitabatake, Akira, Hattori, Yuichi
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573108/
https://ncbi.nlm.nih.gov/pubmed/11786479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704444
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