Preclinical human models and emerging therapeutics for advanced systemic mastocytosis

Mastocytosis is a term used to denote a group of rare diseases characterized by an abnormal accumulation of neoplastic mast cells in various tissues and organs. In most patients with systemic mastocytosis, the neoplastic cells carry activating mutations in KIT. Progress in mastocytosis research has...

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Detalhes bibliográficos
Publicado no:Haematologica
Main Authors: Arock, Michel, Wedeh, Ghaith, Hoermann, Gregor, Bibi, Siham, Akin, Cem, Peter, Barbara, Gleixner, Karoline V., Hartmann, Karin, Butterfield, Joseph H., Metcalfe, Dean D., Valent, Peter
Formato: Artigo
Idioma:Inglês
Publicado em: Ferrata Storti Foundation 2018
Assuntos:
Review Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278969/
https://ncbi.nlm.nih.gov/pubmed/29976735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2018.195867
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