Lung Cancer Survival and Functional Polymorphisms in MBL2, an Innate-Immunity Gene

BACKGROUND: The relationship among chronic inflammation, innate immunity, and cancer is well established. Mannose-binding lectin (MBL) is a key player in innate immunity. Five polymorphisms in the promoter and first exon of the MBL2 gene alter the expression and function of MBL in humans and are ass...

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Bibliographic Details
Published in:J Natl Cancer Inst
Main Authors: Pine, Sharon R., Mechanic, Leah E., Ambs, Stefan, Bowman, Elise D., Chanock, Stephen J., Loffredo, Christopher, Shields, Peter G., Harris, Curtis C.
Format: Artigo
Language:Inglês
Published: 2007
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278934/
https://ncbi.nlm.nih.gov/pubmed/17848669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jnci/djm128
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