Association of MTHFR gene polymorphisms with breast cancer survival

BACKGROUND: Two functional single nucleotide polymorphisms (SNPs) in the 5,10-methylenetetrahydrofolate reductase (MTHFR) gene, C677T and A1298C, lead to decreased enzyme activity and affect chemosensitivity of tumor cells. We investigated whether these MTHFR SNPs were associated with breast cancer...

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Detalhes bibliográficos
Main Authors: Martin, Damali N, Boersma, Brenda J, Howe, Tiffany M, Goodman, Julie E, Mechanic, Leah E, Chanock, Stephen J, Ambs, Stefan
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1634868/
https://ncbi.nlm.nih.gov/pubmed/17069650
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-6-257
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