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Biomodulatory Treatment With Azacitidine, All-trans Retinoic Acid and Pioglitazone Induces Differentiation of Primary AML Blasts Into Neutrophil Like Cells Capable of ROS Production and Phagocytosis

Effective and tolerable salvage therapies for elderly patients with chemorefractory acute myeloid leukemia (AML) are limited and usually do not change the poor clinical outcome. We recently described in several chemorefractory elderly AML patients that a novel biomodulatory treatment regimen consist...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Main Authors: Klobuch, Sebastian, Steinberg, Tim, Bruni, Emanuele, Mirbeth, Carina, Heilmeier, Bernhard, Ghibelli, Lina, Herr, Wolfgang, Reichle, Albrecht, Thomas, Simone
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278634/
https://ncbi.nlm.nih.gov/pubmed/30542286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01380
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