Panax notoginseng Saponins Protect Cerebral Microvascular Endothelial Cells against Oxygen-Glucose Deprivation/Reperfusion-Induced Barrier Dysfunction via Activation of PI3K/Akt/Nrf2 Antioxidant Signaling Pathway

Oxidative stress plays a critical role in cerebral ischemia/reperfusion (I/R)-induced blood-brain barrier (BBB) disruption. Panax notoginseng saponins (PNS) possess efficient antioxidant activity and have been used in the treatment of cerebral ischemic stroke in China. In this study, we determined t...

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Bibliografiset tiedot
Julkaisussa:Molecules
Päätekijät: Hu, Shaonan, Wu, Yali, Zhao, Bo, Hu, Haiyan, Zhu, Baochen, Sun, Zongxi, Li, Pengyue, Du, Shouying
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2018
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278530/
https://ncbi.nlm.nih.gov/pubmed/30373188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23112781
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