Panax notoginseng Saponins Protect Cerebral Microvascular Endothelial Cells against Oxygen-Glucose Deprivation/Reperfusion-Induced Barrier Dysfunction via Activation of PI3K/Akt/Nrf2 Antioxidant Signaling Pathway

Oxidative stress plays a critical role in cerebral ischemia/reperfusion (I/R)-induced blood-brain barrier (BBB) disruption. Panax notoginseng saponins (PNS) possess efficient antioxidant activity and have been used in the treatment of cerebral ischemic stroke in China. In this study, we determined t...

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Detaylı Bibliyografya
Yayımlandı:Molecules
Asıl Yazarlar: Hu, Shaonan, Wu, Yali, Zhao, Bo, Hu, Haiyan, Zhu, Baochen, Sun, Zongxi, Li, Pengyue, Du, Shouying
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI 2018
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278530/
https://ncbi.nlm.nih.gov/pubmed/30373188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23112781
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