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Panax notoginseng Saponins Protect Cerebral Microvascular Endothelial Cells against Oxygen-Glucose Deprivation/Reperfusion-Induced Barrier Dysfunction via Activation of PI3K/Akt/Nrf2 Antioxidant Signaling Pathway

Oxidative stress plays a critical role in cerebral ischemia/reperfusion (I/R)-induced blood-brain barrier (BBB) disruption. Panax notoginseng saponins (PNS) possess efficient antioxidant activity and have been used in the treatment of cerebral ischemic stroke in China. In this study, we determined t...

詳細記述

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書誌詳細
出版年:Molecules
主要な著者: Hu, Shaonan, Wu, Yali, Zhao, Bo, Hu, Haiyan, Zhu, Baochen, Sun, Zongxi, Li, Pengyue, Du, Shouying
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278530/
https://ncbi.nlm.nih.gov/pubmed/30373188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23112781
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