Imidazo[1,2-b]pyrazole-7-carboxamides Induce Apoptosis in Human Leukemia Cells at Nanomolar Concentrations

Leukemia, the malignancy of the hematopoietic system accounts for 10% of cancer cases with poor overall survival rate in adults; therefore, there is a high unmet medical need for the development of novel therapeutics. Eight imidazo[1,2-b]pyrazole-7-carboxamides have been tested for cytotoxic activit...

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Publicado en:Molecules
Main Authors: Szebeni, Gábor J., Balog, József A., Demjén, András, Alföldi, Róbert, Végi, Vanessza L., Fehér, Liliána Z., Mán, Imola, Kotogány, Edit, Gubán, Barbara, Batár, Péter, Hackler, László, Kanizsai, Iván, Puskás, László G.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278434/
https://ncbi.nlm.nih.gov/pubmed/30388846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23112845
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