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Virtual Screening, Biological Evaluation, and 3D-QSAR Studies of New HIV-1 Entry Inhibitors That Function via the CD4 Primary Receptor

Human immunodeficiency virus type 1 (HIV-1) is responsible for the majority of HIV infections worldwide, and we still lack a cure for this infection. Blocking the interaction of HIV-1 and its primary receptor CD4 is one strategy for identifying new anti-HIV-1 entry inhibitors. Here we report the dis...

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Detalhes bibliográficos
Publicado no:Molecules
Main Authors: Zhang, Chaozai, Zhang, Huijun, Huang, Lina S., Zhu, Siyu, Xu, Yan, Zhang, Xing-Quan, Schooley, Robert T., Yang, Xiaohong, Huang, Ziwei, An, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6278378/
https://ncbi.nlm.nih.gov/pubmed/30463393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules23113036
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