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Modality selective roles of pro-nociceptive spinal 5-HT(2A) and 5-HT(3) receptors in normal and neuropathic states

Descending brainstem control of spinal nociceptive processing permits a dynamic and adaptive modulation of ascending sensory information. Chronic pain states are frequently associated with enhanced descending excitatory drive mediated predominantly through serotonergic neurones in the rostral ventro...

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Bibliographic Details
Published in:Neuropharmacology
Main Authors: Patel, Ryan, Dickenson, Anthony H.
Format: Artigo
Language:Inglês
Published: Pergamon Press 2018
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277848/
https://ncbi.nlm.nih.gov/pubmed/30240783
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2018.09.028
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