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Spinal 5-HT3 receptor mediates nociceptive effect on central neuropathic pain; possible therapeutic role for tropisetron

OBJECTIVES: To test the analgesic effect of 5-HT-3 receptor antagonist, tropisetron, in a clip compression injury model of spinal cord pain in rats. METHODS: Four weeks post compression of the spinal cord at lumbar level, tropisetron was administered intrathecally at 100 μg and 150 μg dosages. Behav...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Spinal Cord Med
Päätekijät: Nasirinezhad, Farinaz, Hosseini, Marjan, Karami, Zohre, Yousefifard, Mahmoud, Janzadeh, Autosa
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Taylor & Francis 2016
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5072495/
https://ncbi.nlm.nih.gov/pubmed/26338446
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1179/2045772315Y.0000000047
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