Inhibitory killer-cell immunoglobulin-like receptors strengthen CD8(+) T cell-mediated control of HIV-1, HCV and HTLV-1

Killer-cell immunoglobulin-like receptors (KIRs) are expressed predominantly on natural killer cells, where they play a key role in the regulation of innate immune responses. Recent studies show that inhibitory KIRs can also impact adaptive T cell-mediated immunity. In mice and in human T cells in v...

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Udgivet i:Sci Immunol
Main Authors: Boelen, Lies, Debebe, Bisrat, Silveira, Marcos, Salam, Arafa, Makinde, Julia, Roberts, Chrissy h., Wang, Eddie C.Y., Frater, John, Gilmour, Jill, Twigger, Katie, Ladell, Kristin, Miners, Kelly L., Jayaraman, Jyothi, Traherne, James A., Price, David A., Qi, Ying, Martin, Maureen P., Macallan, Derek C., Thio, Chloe, Astemborski, Jacquie, Kirk, Gregory, Donfield, Sharyne M., Buchbinder, Susan, Khakoo, Salim I., Goedert, James J., Trowsdale, John, Carrington, Mary, Kollnberger, Simon, Asquith, Becca
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6277004/
https://ncbi.nlm.nih.gov/pubmed/30413420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciimmunol.aao2892
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