KIR2DL2 Enhances Protective and Detrimental HLA Class I-Mediated Immunity in Chronic Viral Infection

Killer cell immunoglobulin-like receptors (KIRs) influence both innate and adaptive immunity. But while the role of KIRs in NK-mediated innate immunity is well-documented, the impact of KIRs on the T cell response in human disease is not known. Here we test the hypothesis that an individual's K...

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Detalhes bibliográficos
Main Authors: Seich al Basatena, Nafisa-Katrin, MacNamara, Aidan, Vine, Alison M., Thio, Chloe L., Astemborski, Jacquie, Usuku, Koichiro, Osame, Mitsuhiro, Kirk, Gregory D., Donfield, Sharyne M., Goedert, James J., Bangham, Charles R.M., Carrington, Mary, Khakoo, Salim I., Asquith, Becca
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3192839/
https://ncbi.nlm.nih.gov/pubmed/22022261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002270
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