Nonnucleoside Reverse-transcriptase Inhibitor- vs Ritonavir-boosted Protease Inhibitor–based Regimens for Initial Treatment of HIV Infection: A Systematic Review and Metaanalysis of Randomized Trials

Background. Previous studies suggest that nonnucleoside reverse-transcriptase inhibitors (NNRTIs) cause faster virologic suppression, while ritonavir-boosted protease inhibitors (PI/r) recover more CD4 cells. However, individual trials have not been powered to compare clinical outcomes. Methods. We...

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Publicado en:Clin Infect Dis
Main Authors: Borges, Álvaro H., Lundh, Andreas, Tendal, Britta, Bartlett, John A., Clumeck, Nathan, Costagliola, Dominique, Daar, Eric S., Echeverría, Patrícia, Gisslén, Magnus, Huedo-Medina, Tania B., Hughes, Michael D., Huppler Hullsiek, Katherine, Khabo, Paul, Komati, Stephanus, Kumar, Princy, Lockman, Shahin, MacArthur, Rodger D., Maggiolo, Franco, Matteelli, Alberto, Miro, Jose M., Oka, Shinichi, Petoumenos, Kathy, Puls, Rebekah L., Riddler, Sharon A., Sax, Paul E., Sierra-Madero, Juan, Torti, Carlo, Lundgren, Jens D.
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2016
Assuntos:
HIV/AIDS
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276924/
https://ncbi.nlm.nih.gov/pubmed/27090986
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cid/ciw236
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