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Development of Full Sweet, Umami, and Bitter Taste Responsiveness Requires Regulator of G protein Signaling-21 (RGS21)

The mammalian tastes of sweet, umami, and bitter are initiated by activation of G protein-coupled receptors (GPCRs) of the T1R and T2R families on taste receptor cells. GPCRs signal via nucleotide exchange and hydrolysis, the latter hastened by GTPase-accelerating proteins (GAPs) that include the Re...

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Dettagli Bibliografici
Pubblicato in:Chem Senses
Autori principali: Schroer, Adam B, Gross, Joshua D, Kaski, Shane W, Wix, Kim, Siderovski, David P, Vandenbeuch, Aurelie, Setola, Vincent
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2018
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276893/
https://ncbi.nlm.nih.gov/pubmed/29701767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/chemse/bjy024
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