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Wobble uridine tRNA modification: a new vulnerability of refractory melanoma
The enzymes catalysing the modification of the wobble uridine (U(34)) of tRNAs (U(34)-enzymes) play an important role in tumor development. We have recently demonstrated that the U(34)-enzymes are crucial in the survival of glycolytic melanoma cultures through a codon-specific regulation of HIF1α mR...
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| Veröffentlicht in: | Mol Cell Oncol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6276846/ https://ncbi.nlm.nih.gov/pubmed/30525092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1513725 |
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