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Cisplatin resistance coupled to enhanced sensitivity to metabolic interventions

Specific metabolic alterations have recently been observed in cisplatin-resistant cancers. As a result, cisplatin resistance can be overcome by co-administration of pyridoxine, and cisplatin-resistant cancer cells become exquisitely sensitive to killing by inhibitors of poly(ADP-ribose) polymerase,...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Cell Oncol
Hauptverfasser: Castedo, Maria, Obrist, Florine, Kroemer, Guido
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276841/
https://ncbi.nlm.nih.gov/pubmed/30525097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2018.1526004
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