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Pyridoxal kinase and poly(ADP-ribose) affect the immune microenvironment of locally advanced cancers

Malignant cells adapt to the hostile tumor microenvironment by escaping from, or actively suppressing, anticancer immune responses. In the past, we reported that reduced synthesis of active vitamin B6 (due to downregulation of pyridoxal kinase) or overactivation of poly(ADP-ribose) polymerase confer...

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Publicat a:Oncoimmunology
Autors principals: Joseph, Adrien, Pan, Juncheng, Michels, Judith, Kroemer, Guido, Castedo, Maria
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2021
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8274443/
https://ncbi.nlm.nih.gov/pubmed/34290910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2021.1950954
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