Discordance in the Dependence on Kisspeptin Signaling in Mini Puberty vs Adolescent Puberty: Human Genetic Evidence

CONTEXT: Hypothalamic kisspeptin signaling plays a critical role in the initiation and maintenance of reproductive function. Biallelic mutations in the coding sequence of KISS1R (GPR54) have been identified in patients with idiopathic hypogonadotropic hypogonadism, but it is unknown whether bialleli...

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Detaylı Bibliyografya
Yayımlandı:J Clin Endocrinol Metab
Asıl Yazarlar: Shahab, Muhammad, Lippincott, Margaret, Chan, Yee-Ming, Davies, Addie, Merino, Paulina M, Plummer, Lacey, Mericq, Veronica, Seminara, Stephanie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Endocrine Society 2018
Konular:
Case Reports
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6276658/
https://ncbi.nlm.nih.gov/pubmed/29452377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2017-02636
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