Exogenous Kisspeptin Administration as a Probe of GnRH Neuronal Function in Patients With Idiopathic Hypogonadotropic Hypogonadism

CONTEXT: Idiopathic hypogonadotropic hypogonadism (IHH) results from defective synthesis, secretion, or action of GnRH. Kisspeptin is a potent stimulus for GnRH secretion. OBJECTIVE: We probed the functional capacity of the GnRH neuronal network in patients with IHH. PARTICIPANTS: Eleven subjects wi...

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Pubblicato in:J Clin Endocrinol Metab
Autori principali: Chan, Yee-Ming, Lippincott, Margaret F., Butler, James P., Sidhoum, Valerie F., Li, Cindy X., Plummer, Lacey, Seminara, Stephanie B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Endocrine Society 2014
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JCEM Online: Advances in Genetics
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4255107/
https://ncbi.nlm.nih.gov/pubmed/25226293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/jc.2014-2233
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